Etiology, Epidemiological Aspects and Preventive Strategies of Neural Tube Defects
نویسندگان
چکیده
منابع مشابه
Neural tube defects: prevalence, etiology and prevention.
Spina bifida and anencephaly, the common form of neural tube defects, affect approximately 300 000 newborns each year worldwide. The effectiveness of folic acid supplementation in preventing their occurrence or recurrence has been unambiguous since 1991. In general, the prevalence of these abnormalities has decreased in the past 20 to 30 years because of periconceptional folate supplementation,...
متن کاملStrategies for Prevention of Neural Tube Defects
Neural tube defects (NTDs) are congenital malformations of the brain and spinal cord caused by the failure of neural tubes to close between 21 and 28 days after conception (Sadler, 2005). Any disruption of neurulation during or prior to this time may result in a defect or failure of neural tube closure. Non-invasive prenatal diagnostic testing by ultrasound and maternal serum screening, which s...
متن کاملImplication of Genetic Factors in Neural Tube Defects Etiology
Neural tube defects are a group of developmental abnormalities that results from failure of fusion of the caudal neural tube, representing one of the most common group of malformations of human structure. The etiology is thought to be multifactorial in the vast majority of the cases, but other possible causes are heterogeneous and include chromosome abnormalities, single gene disorders and tera...
متن کاملTime trends in neural tube defects prevalence in relation to preventive strategies: an international study.
OBJECTIVE To examine time trends in neural tube defects (NTD) prevalence from 1987 to 1996 in relation to the primary prevention policies for folic acid supplementation strategies in different countries. DESIGN Retrospective time trends analysis of NTD prevalence. SETTING 11 birth defect registries of congenital malformations participating in the International Clearinghouse for Birth Defect...
متن کاملEpidemiologic aspects of neural tube defects in South East Iran.
OBJECTIVE To investigate the rate of neural tube defects (NTDs) and their relation to gender, maternal age, consanguineous marriage, season, and drug consumption in Birjand, Iran. METHODS This research was carried out on 16,785 live or stillborn newborns in Birjand, Iran from April 1997 to December 2001. RESULTS The rate of NTDs was 2.97 per 1000. This rate was 1.97 per 1000 in males, and 3...
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ژورنال
عنوان ژورنال: Scholars Journal of Applied Medical Sciences
سال: 2020
ISSN: 2347-954X,2320-6691
DOI: 10.36347/sjams.2020.v08i09.031